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Links are provided here to some Society of Nuclear Medicine (SNM) Practice Management Procedure Guidelines.

The procedure guidelines help to identify those elements of the procedure that are most important in obtaining a high-quality examination, while simultaneously controlling costs.

They are categorized in clinical applications. Please follow the links below to the desired applications.


Scintigraphy using 131I or 123I is used to determine the presence and extent of residual functioning thyroid tissue shortly post-thyroidectomy and, after 131I ablation, to detect the presence and location of functioning thyroid cancer, recurrences and/or metastases 18F-FDG PET may be helpful for patients with a rising serum thyroglobulin and negative or minimal iodine uptake. Other radiopharmaceuticals such as 201Tl and 99mTc sestamibi may also provide useful information.

Thyroid uptake determination is the measurement of the fraction of an administered amount of radioactive iodine that accumulates in the thyroid at selected times following ingestion. Thyroid uptake can be determined, less accurately, using intravenously administered 99mTc-pertechnetate and a gamma camera.

Parathyroid scintigraphy is commonly performed using 99mTc-sestamibi in dual-isotope studies with 99mTc pertechnetate/99mTc-sestamibi or 99mTc pertechnetate/201Tl  combinations. In the dual-isotope studies the pertechnetate image is subtracted from the 201Tl or 99mTc-sestamibi image, and what remains is potentially a parathyroid adenoma.

Thyroid scintigraphy is a procedure producing one or more planar images of the thyroid obtained after intravenous injection of 99mTc- pertechnetate or after the oral ingestion of radioactive iodine 131I.